What Are PARP Inhibitors? PARP inhibitors (often called PARPi) are cancer medicines you take as pills. PARP is a protein your cells use to fix small breaks in their DNA. PARP inhibitors block this repair process. When cancer cells can’t fix their DNA damage, they may...
Clinical Trials & Research
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Learn how prostate cancer clinical trials and research help improve prevention, detection, and treatment. Find information on how trials work, who may be eligible, and how to find prostate cancer clinical trials near you.
Live Fireside Chat: Options for Men with Advanced Prostate Cancer
Join Dr. Keith Crawford and Dr. David Einstein, who was ranked among the top prostate cancer oncologists in the country by Newsweek in 2024 and is an investigator of the Phase 3 XALute trial, as he explains: What the study drug xaluritamig does to help the immune...
T-Cell Engager Therapy for Prostate Cancer: An Easy-to-Understand Guide
Prostate cancer is often treatable. Many people do well with surgery, radiation, or hormone therapy. However, sometimes the cancer comes back. Sometimes it spreads to other parts of the body. When that happens, doctors and researchers look for new options. One option...
Targeted Cancer Treatments: What to Know About ADCs in Prostate Cancer
Antibody-drug conjugates (ADCs) are a newer type of cancer treatment designed to target cancer cells more directly. An ADC works like a guided delivery system: The antibody finds and attaches to a specific protein on a cancer cell. A linker holds the parts together....
The Role of Epigenetics in Prostate Cancer: Key Facts for Men
Epigenetics refers to how the body turns genes on or off without changing the DNA itself. Think of DNA as a cookbook: cancer doesn't rewrite the recipes—it adds "sticky notes" telling cells which pages to use or ignore. These epigenetic notes act like switches. In...
Immuno-Oncology: The Next Step in Care for Men Living with Prostate Cancer
Watch Now on PHEN TV Immuno-oncology is transforming how doctors treat prostate cancer — and giving men living with the disease new hope. In this PHEN TV program, experts explain how immunotherapies work by helping your body’s immune system find and destroy prostate...
Realizing the Benefits of Immunotherapy Treatment for Black Prostate Cancer Patients
Black men with advanced prostate cancer have a greater chance of survival after immunotherapy treatment, according to a Duke Cancer Institute study. While several immunotherapy treatments for multiple myeloma and other hematologic cancers are now standard of care,...
Beyond the Clinical Trial: What Real World Evidence Means for Your Prostate Cancer Journey
On Wednesday, May 14, 2025, the PHEN Managing Prostate Cancer Survivorship Meeting and Webinar featured a fireside chat with Dr. Sabree Burbage, PharmD, MPH, Associate Director of RWE in S/T Oncology at Johnson & Johnson, and Dr. Keith Crawford, MD, PhD, Director...