The Trumpet Registry

The TRUMPET registry is looking at how prostate cancer is treated across the United States (U.S.). It is also exploring how treatments for prostate cancer can affect daily life and will include about 1,200 men in the U.S. with castration-resistant prostate cancer (CRPC).

The TRUMPET Registry is needed because the treatment options for prostate cancer have advanced significantly in recent years, and researchers want to look more closely at how different treatments are being used by doctors across the United States. The registry will look at how doctors’ decisions and the treatments they prescribe affect the day-to-day lives of the men who receive them. We hope this information may help improve the care of men with advanced prostate cancer in the future.

A “registry” is a way of collecting clinical and health related information about people with specific medical conditions and/or who are receiving specific treatments. Registries are set up to look at how FDA approved medical treatments are used in everyday life, and they provide important information that cannot be found in any other way. Unlike clinical trial studies, registries are not designed to test potential new medical treatments. They simply collect information about treatments that are already being used, allowing doctors to see how well they work in a “real-world” setting of care. 

The TRUMPET Registry is for men whose prostate cancer progressed (i.e. it has grown or spread) despite use of hormonal treatments to lower their PSA.  Known as castration-resistant prostate cancer, this disease progression may require different treatment options, which can be discussed with the treating physician.

Upon enrolling in TRUMPET, information will be confidentially collected at routine medical visits and through health surveys.  CRPC patients may also have their caregivers take part, and complete health surveys, if they wish. It is hoped that this registry will help guide treatment decisions in the future by assessing:

• How doctors use prostate cancer medications and other treatments

• How prostate cancer and its treatment affects people’s lives

• Why people stop or change treatments

Registries work best when people are followed for many years. This helps researcher to learn as much as possible about the effects of different treatments over time. Those that take part in the TRUMPET Registry, will be involved for up to 4 years or until the registry is closed.

CRPC patients will also be asked to complete questionnaires about their health after enrolling into the registry and every 3 months. Caregivers who participate will complete questionnaires at the beginning of the registry and every 6 months Participants will receive a modest compensation for their time spent completing each set of questionnaires.

For more information please contact or visit www. (NCT02380274).

To inquire about registering at participating study centers, please contact Astellas Scientific & Medical Affairs by calling (800) 888-7704, extension 5473, or emailing 

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