Clinical Trials
High Risk Prostate Cancer

This Information is provided to help patients identify clinical trials for educational purposes and not to recruit patients for any specific trials. Patients should consult with their personal doctor and the trial sponsors for additional information on trials of interest.

Study to evaluate immunotherapy in combination with radiation in prostate cancer patients

Number: NCT01436968
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 3
Sponsor(s): Advantagene, Inc.
Sponsor Trial Information
Trial Location(s) and Contact(s)
Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in Novartis-sponsored Studies

Number: NCT01794793
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 4
Sponsor(s): Novartis Pharmaceuticals|Novartis
Sponsor Trial Information
Trial Location(s) and Contact(s)
A Phase 1/2 Study of In Situ Vaccination With Tremelimumab and IV Durvalumab Plus PolyICLC in Subjects With Advanced, Measurable, Biopsy-accessible Cancers

Number: NCT02643303
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 1|Phase 2
Sponsor(s): Ludwig Institute for Cancer Research|MedImmune LLC|Cancer Research Institute, New York City
Sponsor Trial Information
Trial Location(s) and Contact(s)
Use of Ligand-Inducible Autologous T Cells Engineered to Target PSCA on Tumor Cells in Selected Advanced Solid Tumors

Number: NCT02744287
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 1|Phase 2
Sponsor(s): Bellicum Pharmaceuticals
Sponsor Trial Information
Trial Location(s) and Contact(s)
Apalutamide and Leuprolide in Intermediate and High-risk Prostate Cancer

Number: NCT02770391
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: 2
Sponsor(s): Case Comprehensive Cancer Center
Sponsor Trial Information
Trial Location(s) and Contact(s)
Study of Nanoparticles and Radiation or Radiation With Brachytherapy for Prostate Cancer

Number: NCT02805894
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): Nanobiotix
Sponsor Trial Information
Trial Location(s) and Contact(s)
Apalutamide With or Without Abiraterone, Hormone, and Prednisone in Treating High-Risk Patients Undergoing Surgery

Number: NCT02949284
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): Rutgers, The State University of New Jersey|National Cancer Institute (NCI)
Sponsor Trial Information
Trial Location(s) and Contact(s)
A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study

Number: NCT02960022
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): Astellas Pharma Global Development, Inc.|Pfizer|Astellas Pharma Inc
Sponsor Trial Information
Trial Location(s) and Contact(s)
Trial of Androgen Deprivation Therapy and Radiation Versus Radiation Prostate Cancer

Number: NCT03056638
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 3
Sponsor(s): Memorial Sloan Kettering Cancer Center|Ferring Pharmaceuticals|University of Texas Southwestern Medical Center|University of Michigan
Sponsor Trial Information
Trial Location(s) and Contact(s)
Study of Screening Method for Detection of Metastasis Among High-risk Prostate Cancer Patients

Number: NCT03081884
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): Emory University|National Cancer Institute (NCI)
Sponsor Trial Information
Trial Location(s) and Contact(s)
A Study to Evaluate Relugolix in Men With Advanced Prostate Cancer

Number: NCT03085095
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 3
Sponsor(s): Myovant Sciences GmbH
Sponsor Trial Information
Trial Location(s) and Contact(s)
PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors

Number: NCT03149549
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 1|Phase 2
Sponsor(s): CytomX Therapeutics
Sponsor Trial Information
Trial Location(s) and Contact(s)
Study to Assess Safety, Tolerability and Clinical Activity of BGB-290 in Combination With Temozolomide (TMZ) in Subjects With Locally Advanced or Metastatic Solid Tumors

Number: NCT03150810
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 1|Phase 2
Sponsor(s): BeiGene|Myriad Genetics, Inc.
Sponsor Trial Information
Trial Location(s) and Contact(s)
Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors

Number: NCT03333616
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): Dana-Farber Cancer Institute|Bristol-Myers Squibb
Sponsor Trial Information
Trial Location(s) and Contact(s)
Radiation Therapy With or Without Apalutamide in Treating Patients With Prostate Cancer

Number: NCT03371719
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): NRG Oncology|National Cancer Institute (NCI)
Sponsor Trial Information
Trial Location(s) and Contact(s)
Multi-arm Multi-modality Therapy for Very High Risk Localized and Low Volume Metastatic Prostatic Adenocarcinoma

Number: NCT03436654
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): Memorial Sloan Kettering Cancer Center|Dana-Farber Cancer Institute
Sponsor Trial Information
Trial Location(s) and Contact(s)
Study of PSMA-targeted 18F-DCFPyL PET/CT for the Detection of Clinically Significant Prostate Cancer

Number: NCT03471650
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins|Progenics Pharmaceuticals, Inc.
Sponsor Trial Information
Trial Location(s) and Contact(s)
Rucaparib and Nivolumab in Patients With Prostate or Endometrial Cancer

Number: NCT03572478
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 1|Phase 2
Sponsor(s): University of Chicago|Bristol-Myers Squibb|Clovis Oncology, Inc.
Sponsor Trial Information
Trial Location(s) and Contact(s)
Study of VERU-944 to Ameliorate Hot Flashes in Men With Advanced Prostate Cancer

Number: NCT03646162
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): Veru Inc.
Sponsor Trial Information
Trial Location(s) and Contact(s)
Nivolumab and BMS-986253 for Hormone-Sensitive Prostate Cancer (MAGIC-8)

Number: NCT03689699
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 1|Phase 2
Sponsor(s): Charles G. Drake|Bristol-Myers Squibb|Columbia University
Sponsor Trial Information
Trial Location(s) and Contact(s)
Improving Quality of Life of Prostate Cancer Survivors With Androgen Deficiency

Number: NCT03716739
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): Dana-Farber Cancer Institute|National Institute on Aging (NIA)
Sponsor Trial Information
Trial Location(s) and Contact(s)
A Study of Pembrolizumab Plus Androgen Receptor Targeting Prior to Prostatectomy for High Risk Patients

Number: NCT03753243
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: 2
Sponsor(s): Merck Sharp & Dohme Corp.|Astellas Pharma Inc|Portland VA Medical Center
Sponsor Trial Information
Trial Location(s) and Contact(s)
A Study of Apalutamide in Participants With High Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

Number: NCT03767244
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 3
Sponsor(s): Janssen Research & Development, LLC
Sponsor Trial Information
Trial Location(s) and Contact(s)
Conventional ADT w/ or w/Out Abiraterone Acetate + Prednisone and Apalutamide Following a Detectable PSA After Radiation and ADT

Number: NCT03777982
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 3
Sponsor(s): Dana-Farber Cancer Institute|Janssen Scientific Affairs, LLC
Sponsor Trial Information
Trial Location(s) and Contact(s)
A Study Evaluating the Safety, Pharmacokinetics and Efficacy of Ipatasertib Administered in Combination With Rucaparib in Participants With Advanced Breast, Ovarian Cancer, and Prostate Cancer.

Number: NCT03840200
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 1|Phase 2
Sponsor(s): Hoffmann-La Roche
Sponsor Trial Information
Trial Location(s) and Contact(s)
Neoadjuvant Dupilumab in Men With Localized High-Risk Prostate Cancer

Number: NCT03886493
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins|Regeneron Pharmaceuticals
Sponsor Trial Information
Trial Location(s) and Contact(s)
Aspirin and Rintatolimod With or Without Interferon-alpha 2b in Treating Patients With Prostate Cancer Before Surgery

Number: NCT03899987
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): Roswell Park Cancer Institute|National Cancer Institute (NCI)|Hemispherx Biopharma
Sponsor Trial Information
Trial Location(s) and Contact(s)
A Trial of BXCL701 and Pembrolizumab in Patients With Small Cell Neuroendocrine Prostate Cancer

Number: NCT03910660
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 1|Phase 2
Sponsor(s): BioXcel Therapeutics Inc
Sponsor Trial Information
Trial Location(s) and Contact(s)
Prostate Specific Membrane Antigen (PSMA)-Based PET Imaging of High Risk Prostate Cancer

Number: NCT03976843
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): National Cancer Institute (NCI)|National Institutes of Health Clinical Center (CC)
Sponsor Trial Information
Trial Location(s) and Contact(s)
Perioperative Atezolizumab With MVA-BN-Brachyury and PROSTVAC For Intermediate-Risk And High-Risk Localized Prostate Cancer

Number: NCT04020094
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): University of Utah|Bavarian Nordic|Genentech, Inc.
Sponsor Trial Information
Trial Location(s) and Contact(s)
A Study to Evaluate Rucaparib in Patients With Solid Tumors and With Deleterious Mutations in HRR Genes

Number: NCT04171700
PHEN Patient Summary
ClinicalTrials.gov Information
Trial Phase: Phase 2
Sponsor(s): Clovis Oncology, Inc.
Sponsor Trial Information
Trial Location(s) and Contact(s)

Total: 31 Clinical Trials

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