The Prostate Health Education Network: Prostate Health Education and Awareness

PHEN Clinical Trials Rally

Increasing the participation of African American men in prostate cancer clinical trials through education, awareness, support and collaborations. This portal provides clinical trials background information, details for specific trials, personal stories and other resources to support the Rally.

This information is not intended as medical advice for patients. Patients should consult their medical doctor for advice and recommendations about specific clinical trials.

"We must not be left behind with new prostate cancer treatments." PHEN president and founder Thomas A. Farrington talks about his prostate cancer journey and the importance of African American men participating in clinical trials. Information	Understanding the possible benefits for patients when participating in a clinical trial. Clinical trials offer important and unique benefits to patients. Information
What Are Clinical Trials? Information that all patients need to know when considering enrolling into a clinical trial. Information	Dr. J. Carter Presents Clinical Trials 101 Dr. Carter's brief video presentations provide basic information for patients to better understand clinical trials. Information
A Clinical Trials Guide for Patients Patient information on why clinical trials matter, how clinical trials work, what to expect, myths and facts. Information provided by Sanofi. Information	PSMAfore The clinical trial objective is to determine whether treatment with PluvictoTM will slow or stop the progression prostate cancer in men with progressive PSMA-positive mCRPC compared to participants treated with ARDT. Information
PSMAddition A Study to evaluate the radioligand 177Lu-PSMA-617 (PluvictoTM) in patients with naīve or minimally treated PSMA-positive metastatic hormone sensitive prostate cancer (mHSPC) (PSMAddition) Information	Acapatamab This study is investigating the safety and effects (good or bad) of using acapatamab alone or with pembrolizumab (Keytruda) to treat metastatic castration resistant prostate cancer (mCRPC), which has spread to other parts of the body and is resistant to standard hormonal therapies. Information
AMG 509 This clinical trial is for patients who have metastatic castration resistant prostate cancer (mCRPC) and failed to respond to abiraterone acetate or enzalutamide (but not both) and to taxane-based chemotherapy. Information	AMG 757 This study evaluates the safety and the maximum dose that can be handled by patients in this trial. Information
CheckMate 7DX The purpose of this study is to test the safety and efficacy of nivolumab with docetaxel in men with advanced castration resistant prostate cancer (mCRPC), who have progressed after second-generation hormonal manipulation. Information	Amplitude The AMPLITUDE study is looking for men with newly diagnosed metastatic prostate cancer. Information
APA RP The APA RP study is looking for men with prostate cancer at high risk of metastasis and who have recently undergone or are planning to undergo radical prostatectomy (RP) surgery. Information	PROTEUS The PROTEUS study is a randomized, double-blind, placebo-controlled, phase 3 study of an investigational drug in subjects with high-risk, localized or locally advanced prostate cancer who are candidates for radical prostatectomy. Information
SPLASH This trial is for male patients with metastatic castration-resistant prostate cancer (mCRPC) who have progressed following treatment with androgen receptor axis-targeted therapy (ARAT) but who haven't yet received chemotherapy for mCRPC. Information	P-PSMA-101 This clinical trial is for patients with metastatic castration-resistant prostate cancer (mCRPC) that has worsened despite having received hormonal and chemotherapeutic treatments. Information
TALAPRO-3 This trial is for people with metastatic castration-sensitive prostate cancer (mCSPC) and DNA damage repair (DDR) gene alteration. Information	Low Risk Prostate Cancer Clinical trials for patients who are diagnosed with low risk prostate cancer (Gleason 6). Patients may be interested in active surveillance or making a decision to begin active treatment. Information
Intermediate Risk Prostate Cancer Clinical trials for patients who are diagnosed with intermediate risk prostate cancer (Gleason 7). Patients may be interested in active surveillance or making a decision to begin active treatment. Information	High Risk Prostate Cancer Clinical trials for patients diagnosed with high risk prostate cancer (Gleason 8 - 10). Patients may be deciding on an active treatment protocol. Information
Biochemical Recurrence of Prostate Cancer Clinical trials for patients who have a recurrence of prostate cancer following primary treatment with surgery or radiation. These patients have not yet begun treatment with androgen deprivation therapy or are interested in quality of life studies. Information	Non-Metastatic Castration Resistant Prostate Cancer (nMCRPC) Clinical trials for patients whose PSA rises while they are on androgen deprivation therapy but prostate cancer has not metastasized. Information
Metastatic Castration Resistant Prostate Cancer (MCRPC) Clinical trials for patients diagnosed with metastatic prostate cancer that no longer responds to androgen deprivation treatment. Patients who are seeking treatment options following a diagnosis of MCRPC. Information	Metastatic Castration Sensitive Prostate Cancer (MCSPC) Clinical trials for patients with prostate cancer which has spread to other parts of the body but still respond to medical or surgical treatments that lowers testosterone Information